Mesothelioma and Non Asbestos Exposure
The majority of mesothelioma cases occur on the lung linings as well as the abdomen. This rare cancer also can form in the tissue lining the heart (pericardium) or testes.
Asbestos exposure is the primary risk factor for mesothelioma. Some people with mesothelioma have no prior history of exposure to asbestos.
Exposure to Asbestos
Asbestos, a rock of natural origin, was used in the past for industrial and construction products throughout the globe. The workers in asbestos-related industries handled the material on a regular basis and were at risk of exposure. Asbestos particles can be stuck in the lungs which can cause lung diseases. This is known as asbestosis. Over time, the fibers trapped in the lungs may cause mesothelioma. Asbestos fibers can be breathed in or consumed through the skin. The risk of developing mesothelioma and other asbestos-related illnesses increases with exposure.
Most cases of mesothelioma stem from exposure to occupational toxins. Asbestos was used in many trades, including construction insulation electrical work, automotive maintenance and pipefitting. These professions are usually dominated by men and, as a result mesothelioma cases involving males account for 75-80% of all reported cases. The gradual elimination of asbestos in the United States, and other first-world nations, has reduced occupational contamination. This has caused an increase in cases with non-occupational exposure increasing.
Non-occupational Mesothelioma occurs when asbestos is released at the workplace, or is found at home or in schools. Secondhand exposure can also cause it, such as when a family member touches the clothes worn by an asbestos worker. People who are exposed to this kind of exposure may have symptoms such as breathlessness or chest pain, which is often mistaken as heart or lung conditions.
Certain studies have linked mesothelioma to non-occupational exposures, but the results differ. Many of these studies have been conducted on a limited sample size, and between-study the degree of heterogeneity is high. It is imperative to conduct more studies to confirm the connection between non-occupational asbestos exposure and mesothelioma.
Those with non-occupational exposure should discuss their asbestos medical history with their physician. If they are concerned, they should seek for mesothelioma screening and a referral to a specialist. Mesothelioma specialists are able to provide patients with the most effective treatment and care options to improve their odds of survival. They will analyze medical records and conduct imaging tests to determine the disease. They will also offer advice on how to file a mesothelioma lawsuit to receive compensation from an asbestos trust fund.
Secondhand Exposure
Asbestos exposure is the most common cause of mesothelioma. However, it's not the only one. There is some evidence that people who haven't had exposure to asbestos or worked in industries with asbestos-related activities can still develop mesothelioma. This is referred to as secondary or non-occupational exposure.
Asbestos fibers are extremely small and they can stick to clothing, hair skin, and other surfaces. As a result, workers could bring the hazardous fibers home with them on their work clothes, and then transfer them to family members. These asbestos fibers could be swallowed or inhaled which can lead to mesothelioma.
This type of mesothelioma is more prevalent in women, and it usually occurs in the lungs. However, it could also be found in the abdomen and the chest wall. The most commonly reported sign is a shortness of breath (dyspnea), and it can be associated with other symptoms such as fluid in the lungs, or a swelling in the scrotum.
The mesothelioma that develops in the lungs is known as mesothelioma pleural. Mesothelioma affecting the stomach or chest wall is known as mesothelioma peritoneal. People suffering from this kind of mesothelioma might experience a variety of symptoms, including abdominal pain, breathing problems and constipation.
Several studies have reported that even those who have no prior history of occupational exposure to asbestos can still develop mesothelioma as a result of exposure to asbestos through secondhand fibers. These individuals typically resided with someone who was exposed to asbestos. They could have touched the clothing of the asbestos worker, or had other contact with the asbestos worker.
Veterans are at a higher risk of developing mesothelioma due to asbestos that was widely used in military bases as well as vehicles and ships. The Navy is at a higher risk, as asbestos was used in the hull and gun turrets on ships to guard them from fire. Asbestos was also often taken home by sailors after their work aboard ships that had been infected with asbestos.
Environmental Exposure
A variety of materials have been linked to mesothelioma. Nevertheless, the disease is often linked to exposure to asbestos. Asbestos, a naturally occurring mineral, was used in manufacturing for many years. The mineral is heat-resistant and durable, making it ideal for insulation, brakes, shingles flooring, and many other products. Asbestos is broken down into dust, which can be inhaled and swallowed. The asbestos fibers can remain in the stomach and lungs for a long time, triggering symptoms of mesothelioma.
The most frequently reported mesothelioma symptoms are chest pain, abdominal discomfort and trouble breathing. Asbestos exposure can cause these symptoms to persist for up to 60 years. It is essential to consult a doctor when you experience these symptoms. It is also important to inform your doctor about your previous history of asbestos. This will prevent a misdiagnosis and ensure you receive the right treatment.
The most frequent victims of mesothelioma from asbestos exposure are those who worked directly with asbestos but it is possible for loved relatives to be affected. This is referred to as secondary exposure. Family members can inhale or ingest asbestos fibers from the work shoes, clothing or other tools. They could be sprayed on the home by someone who is wearing or having their hair. This is the reason mesothelioma sufferers and their families should always ensure that they clean their clothing after working around asbestos.
There is a significant body of literature that shows a relationship between nonasbestos exposure and mesothelioma. However there aren't any definitive conclusions yet about the role of other agents. There is evidence to suggest that the chlorosotile and erionite zeolites, can cause mesothelioma. Erionite is present in soil and rocks of certain parts in Turkey where the risk of pleural mesothelioma is high.
Research into the relationship between mesothelioma and exposure to nonasbestos is ongoing. Funnel plots indicate the possibility of bias in publications and there is a large level of heterogeneity between studies. It is evident that asbestos exposure is the biggest mesothelioma-related risk factor.
Genetics
The mesothelioma rare disease occurs when malignant cells of mesothelium multiply uncontrollably and invade surrounding tissues. It can also spread throughout the body via the blood or lymphatic system, affecting other organs. Asbestos is the primary cause, but it's not the only cause. The condition can also be triggered by other genetic and environmental factors.
In some instances, mesothelioma has occurred in people who had no direct exposure to asbestos. These people are called non-occupational mesothelioma patients. They are typically exposed indirectly by the handling of harmful household items or clothing by anyone who was exposed to asbestos in their home. It is possible to be diagnosed with mesothelioma after inhaling asbestos fibers from the clothing of a family member. Studies have shown that these kinds of mesothelioma patients tend to have longer latency times and are more likely to be diagnosed in wives than in husbands.
Scientists are currently investigating the possibility that a genetic predisposition to mesothelioma could play a role in the development of the disease. Recent studies have demonstrated that mutations in BAP1, a gene, increases the risk of mesothelioma in those who are exposed to asbestos. This finding is significant as it could lead to improved screening methods for those who are at high risk of developing mesothelioma.
Researchers have discovered that a range of genes are linked to mesothelioma. These genes are frequently altered in mesothelioma and suppress the growth of tumors. These genes include the large homolog of tumor suppressor 2 (LATS2) and the NF2.
rialto asbestos law firm of the disease can increase the risk. Certain genes, like BAP1, for instance, BAP1 that are passed down from parents. Asbestos was a common ingredient in the military for a number of years, and veterans have the highest mesothelioma rates in comparison to other occupational groups. People who worked on ships and in the Navy were at the highest risk due to asbestos exposure in the construction of ships, insulation and fireproofing materials.